Well the 3.3v rail is used by most of the IC's on the motherboard so if your power supply has a dodgy 3.3v rail then they aren't going to function properly or at all, causing the system to fail POST or not even get to it. One cause of such a faliure could be a broken or damaged sense cable on the PSU meaning that the PSU can't sense the 3.3v rail correctly. It does sound like you need a new PSU and hope the motherboard is okay.
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