Would you...

It might be alright, it might not. Same thing with mixing RAM on any platform, tbh.


What is your usage of the PC?

If you're running out of memory right now then yes, you're very unlikely to notice the timings in games (a few fps at most), but if you're running out it can have a big impact in overall smoothness and especially the stutters & lows.
I was playing Crusader Kings 3 earlier and during some combat it was getting almost unplayable and I noticed my RAM usage was really high in Afterburner, possibly capping out or very close to.
 
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