hardc0re_tid - Yes I will be getting one for now, maybe another later.
These are not for gaming, as I think all the evidence shows games currently just don't benefit from this number of cores.
Me, this is a folding tool. One of my passions and hobbies is folding and because I can only run 4 machines in my very small home office, I need more cores than boxes. I currently have 4x quads + 1 Mac Pro 8x2.8. I have only just got the mac and it screams with a 1600fsb processor. (one of the quads is at my work! - I am limited due to heat)
Now, if I could replace some of the quads, then I will be very happy. I am holding out a little, just to see how the few motherboard differ. I know there are at least 2 or 3 dual ST boards coming.
I will also be going for the more budget xeon's, the Extreme ones are just a waste, IMHO

So if I can get something around the 2.6 / 2.8 then overclock it to 3.2, that will kick 455.
Sure, some may feel this is a waste, but for me, its about getting the most PPD per machine per day. Of course, this is until the new xeon's with CSI inside, those will really rock.
-casw1000
fold4life.com