Ok, so got this today and i'm impressed so far. With no tinkering, the game ran well, and it can run in my native res (1680x1050) on low textures, but looks naf, so I reduced the res to a lower 16:10 one and increased textures and put draw distance to the max allowed. Now it plays well (20-38fps) ingame, and is very playable. I'm enjoying the missions so far too.
This is all with the spec in my sig. My CPU was originally at 2.66GHz and I benchmarked 35fps, and overclocking to 3Ghz saw a 1-2fps increase, not a lot. I'm thinking a new gfx would be good sometime in the new year, but for now, the game is running nicely. No crashes. There is some pop-in, but this is to be expected, esp with my low vid mem, plus it doesn't happen very often. I have all the lastest updates.
Thought i'd share one success story!