Ive done similar - LA to > Palm Springs > Las Vegas - flew to San Fran then drove San Fran to LA along the pacific coast highway.
I loved the epic hugeness of the deserty/plainy areas, quite jaw dropping.
Ive done London to Glasgow loads of time, most as a point to point to get it done but have road tripped it with mates and took 2 days including stop offs.
Also have done London > Paris > Malaga > Cadiz > Tenerife(ferry, not a Lotus Esprit submarine!) in 5 days - was utterly knackering but good fun, done in a Audi 200 Quattro, properly bargetastic.
I kind of did one today - City Of London to Birmingham in just under 2 hours on the CBR, amazed the weather held off, cold but sunny and dry all the way.
Loving the new Battlax BT021 on the front
Road trips are the epic win!
I'll see your road and raise it to the one I drove on below in Nevada 2005.