Eh? So you've turned off UAC to reduce prompts... but then install Comodo and NOD32 security suites. So you're back at square one? Actually that's worse than square one. I can't think of anything worse.
Firstly, I have disabled the defense + security level so I don't get a million pop ups for just trying to open the task manager, so I don't get any pop ups apart from the odd ones for games trying to connect to the internet, devices trying to connect to my PC etc.
Also Nod 32 antivirus (not the smart security) doesn't have any pop ups at all (unless there is a setting or something which you need to enable, but I am pretty sure it doesn't)
Since when does comodo or nod32 prompt you for comfirmation every time you want to install something?
It doesn't depending on the settings that are being used.
Precisely the opposite in my experience.
People that turn it off are advanced users and know what they're doing.
People that leave it on are usually basic users who will easily get suckered into installing an anti-virus recommended by a pop-up. They'll just allow everything and end up infected regardless.
UAC won't protect someone with no common sense. However, Common sense will protect someone, even without UAC.
+ 1, pretty much my opinion as well.
If the user is just a basic user, who doesn't know much about computers/software etc. and only uses the PC for browsing, work (using office or something else) then they might as well leave it on, even though they probably won't know what the setting does

or even what the pop up means
Where as for someone who does know a lot more about the stuff and spend most of there time on the PC messing around with settings, trying different software out etc. downloading a lot of stuff from sites etc. then personally I would say turn it off as your more than likely experienced enough to make those decisions your self and don't need to be told what it is, what it does etc.
But I know some people are just paranoid about privacy, security etc. as I know a few people who run real time programs, 1 anitvirus, 1 firewall, 2 spyware programs (with the pop ups constantly on, so anything that you want access to, you will get a prompt asking what to do etc.) and then do a scan every day etc.
No matter what anyone says here, no matter how smart, knowledgeable etc. they are, I will not turn UAC on, as I have stated that my PC is working great with it off, no problems what so ever with peerblock, Nod32 anitvirus, comodo firewall and of course the router firewall on and plus a spyware program to do a scan every so often.
Have not had any spyware or viruses ever since my install of windows 7 and I install, uninstall etc. a number of programs everyday, download something every day (legal stuff), however saying that there have been some sites that I visit regularly e.g. one of them is a well known forum that I use for keeping up to date with my spica etc. and as soon as the website loaded up, nod32 antivirus showed a pop up saying that one of the ads that was loaded on that site was a hack, trojan downloader and it was quarantined immediately.
Also one person that I know who has a lot more security programs etc. with the pop ups turned on etc. (although is on XP) has a lot more problems than anyone I know in terms of performance, stability. Has pretty much the same hardware as me and his system is so slow, unresponsive, hangs and might I also mention he caught a virus and a few spyware as well even though he has all that security and it still hasn't done him any favours compared to someone like me with my setup who has had no problems.
So just shows no matter how much protection you have, if your not smart/knowledgeable enough then it proves to be pretty useless in the end.