How will the end game work in D3?
In D2, it was re-running Baal to get better/specific loot for your type of build while (very) slowling levelling up.
In D3, it seems that bosses aren't the best place for loot anymore - so will it be running Inferno difficulty from start to finish?
I do worry that the lack of 'builds' will ruin the replayability a bit. Most of the fun I had in D2 was creating multiple characters to try multiple builds, but thats gone now, as is the massive level goal - which just leaves the loot....