Even in the East, the Russians make up for just 30% of the population - think about that for a second. I would guess there are some areas in England where Indians reached 20% or so. Would you support their right of self determination if they suddently decided they want to join India?
What does removing all other groups even mean?
The vote that resulted in a win for the former President has nothing to do with breaking up Ukraine , "self determination" or anything like that.
Those people have families, friends, they don't want Ukraine broken up in pieces, not even the Russians or we'd see them protesting in the hundreds of thousands, like they last winter.
What we're seeing is heavily armed men taking over police stations and city halls which is very similar to how things played out in Crimeea in the early stages. This isn't about self determination, values, or ethnicity. It's about Russia making yet another land grab.