Personally I've found failure rates on disks is very variable. One thing I have noticed over the years is that disks that live on their side tend to fail more frequently than those mounted horizontally. I have read some comments that suggested the 4TB Se produces a lot of vibration, which could be part of it. I'm only using 1 & 2TB versions which are extremely smooth & quiet.
As to the original question though, I'd get whichever was cheapest between the Se and red Pro. @ 4TB the red pro is the obvious choice, 2 & 3TB I'd go with Se. Standard red disks have too low a URE for me, too much risk in the event of a parity rebuild. If I could afford to use Re I would have.