Are drugs a placebo?

paracethomol/ibruprofin/cocodamol etc has literly no effect on me.....If i have some sort of pain or headache, I'm outta luck unless I have some codeine in the house (its damm expensive) and you don't get much in the packets it runs out quick.

If it's a placebo, then how do these drugs work at reducing fever in babies/toddlers who are too young to understand?

Or is the placebo acting on the parents/nurses, making them hallucinate when looking at the thermometer?
Because babys/toddlers havn't had a chance to become resistant to it?
Take something often enough and your body will develop a resistance to it, by the time your an adult its more likely to not effect you at all (something like only 25% of people have any effect from the basic stuff) there is a reason its stupid cheap to buy massive quantity's of it, its not worth anything but people still buy it as they "believe" it helps and it does per the placebo effect which is a very powerful thing.
 
Last edited:
  • Hayfever - tried many, many different drugs both over the counter and also perscribed, has no effect!
My hayfever atm is doing my head in, I've just used 8 tissues to wipe my nose, watery snot just running out of it like a tap and my eyes are itchy as hell, nothing works!

I currently take Fexofenadine (180mg) and Atarax (25mg) daily for my eczema, one of the more useful side-effects of both is that my hayfever isn't a problem at all. :D
 
I think things like headaches are just people whingeing over nothing. I certainly have never had one.

I've taken an aspirin in 2007 after dislocating my shoulder, that did nothing. Went out drinking a few hours later though, alcohol definately numbed it pretty well.
 
I think things like headaches are just people whingeing over nothing. I certainly have never had one.

I've taken an aspirin in 2007 after dislocating my shoulder, that did nothing. Went out drinking a few hours later though, alcohol definately numbed it pretty well.

Alright LAD.
 
Hi

I have never found that any drugs actually make a difference to me when I'm ill or I have a condition.

For example:

  • Headaches - paracethomol - never worked for me
  • Cold/Flu - the usual drugs to reduce the symptoms never work
  • Hayfever - tried many, many different drugs both over the counter and also perscribed, has no effect!
My hayfever atm is doing my head in, I've just used 8 tissues to wipe my nose, watery snot just running out of it like a tap and my eyes are itchy as hell, nothing works!

I think that many drugs (other than specialised drugs) are mostly in effective and people believe in them because of the placebo effect.


No they work just depends on how/why your taking them.

Most of the situations you've described there are self diagnosed bodge jobs.

You don't know why you have your symptoms, you have no ability to treat the root cause so you throw something that is supposed to work at it and hope for the best.
 
Paracetamol do work quite well, but it is a drug that works best while being in the system for a longer time, so taking just 1-2 tablets every now and then will usually not help that much. But it is a damn good thing to use to reduce temperatures in any one (not only kids/toddlers).

And about getting constipation from painkillers, it is a quite known side effect for the majority of the pain killers, unfortunately not a lot of people seem to understand/realise that. I've had to look after quite a few people who comes in with abdominal pains, who then gets pain killers to solve the pain issue. But then the pain is quite often coming due to constipation from the original pain killers the patients are taking :D
 
Since I know its all placebo now that's put my fears of antimicrobial resistance at rest, that wont stop Meropenem exerting its placebo effect.
 
Paracetamol is a very effective painkiller in the right circumstances. When I was in hospital a couple of years ago with a pleural effusion that resulted in sepsis I received oramorph, codeine and paracetamol. In the early stages it was all about the oramorph, but after that paracetamol was actually the most effective pain relief.


thing is people expect paracetamol to just remove the painb, it doesnt.

it makes it forgettable though.

people often take a pracetamol then lie there wallowing in thier missery.

idea is take it then move on with your day and you'll soon forget about the pain
 
Because babys/toddlers havn't had a chance to become resistant to it?
Take something often enough and your body will develop a resistance to it, by the time your an adult its more likely to not effect you at all (something like only 25% of people have any effect from the basic stuff) there is a reason its stupid cheap to buy massive quantity's of it, its not worth anything but people still buy it as they "believe" it helps and it does per the placebo effect which is a very powerful thing.

This post is completely contradictory...

How do you become tolerant to something which according to you does nothing in the first place? Maybe the people it does work on simply haven't built up a tolerance and so rather than the placebo affect it is actually the drug working (obviously it's pretty difficult to prove either way without conducting a proper trial).

Not sure what the fact they are cheap has to do with them being a placebo. They are cheap because they are simple drugs which have been around for decades and are cheap and easy to produce - maybe the fact they are so cheap means some people take them at the first sign of the slightest twinge and so have built up that tolerance, but that doesn't necessarily mean they are a placebo.

That's like saying vodka doesn't get you drunk because an alcoholic can drink a bottle and still be "sober"

thing is people expect paracetamol to just remove the painb, it doesnt.

it makes it forgettable though.

people often take a pracetamol then lie there wallowing in thier missery.

idea is take it then move on with your day and you'll soon forget about the pain

Actually paracetamol isn't hugely affective for things like headaches (ibuprofen is far more effective for that, but does have some issues for asthmatics/people with stomach problems), it is however great for lowering fever and for that horrible shivery feverish ache you get in your muscles with colds/flu
 
ibruprofin ftw, only legal thing that gets rid of head/muscle aches.

Smoking canabis however is the cure for all muscle pain.

My elderly dad has a rare and aggressive form of arthritis that has been eating his skeleton away, he has had various bits replaced (knee's, shoulder, hips) and has been in constant pain for years, Reached the end of pain management and was on enough Tramadol to stop an elephant every day - which caused so many other issues and the poor bloke went through insane cold turkey when he stopped taking them in the end.

So I used to get him some cannabis and bake with it for him, and it helped a lot with all his pains - he just said to me he didn't like the side effects......I was a bit :confused:, what side effects?

"It just makes me want to sit down and do nothing" :D
 
paracethomol/ibruprofin/cocodamol etc has literly no effect on me.....If i have some sort of pain or headache, I'm outta luck unless I have some codeine in the house (its damm expensive) and you don't get much in the packets it runs out quick.
[..]

co-codamol contains codeine. It's just codeine and paracetamol and inert filler to make the tablets big enough. So you're saying that codeine has literally no effect on you and the only thing that works is codeine. Which makes no sense unless you're arguing that due to some peculiarity of your body paracetamol somehow negates codeine or you are somehow getting hold of higher dose codeine-only tablets (which as far as I know aren't legally available in the UK without a prescription).

Are you aware that codeine is addictive and you can build a tolerance to it? It shouldn't be used much, which is why the packets contain relatively few pills. And they're not that expensive if you buy generic. As little a 8p per tablet in Boots, for example. (£2.49 for 32 paracetamol+codeine tablets).
 
co-codamol contains codeine. It's just codeine and paracetamol and inert filler to make the tablets big enough. So you're saying that codeine has literally no effect on you and the only thing that works is codeine. Which makes no sense unless you're arguing that due to some peculiarity of your body paracetamol somehow negates codeine or you are somehow getting hold of higher dose codeine-only tablets (which as far as I know aren't legally available in the UK without a prescription).
.
especially when the paracetamol is in there for the opposite reason, its been shown to enhance the codeine and therefore you can reduce the dose and the side effects.

So much nocebo in here (just like in the hayfever thread, no over the counter works, goes to doctor gets prescribed the most common over the counter medicine and it suddenly works) and so many lacking even basic knowledge in medicine.
 
Many cold and flu remedies are herbal crap which are shown not to work.

Paracetamol and ibuprofen are weak painkillers so frequently don't help.

Codeine has no beneficial effect on many people because they cannot metabolise the drug to morphine, so I can understand people saying it's a placebo. Some other people are extensive metabolisers and are harmed by it. From a safety and efficacy perspective it really makes no sense to use codeine when the metabolite morphine is available.

Unfortunately the UK suffers from bad pain management practices where codeine is used extensively instead of stronger opioids which are safer and more reliable.
 
Back
Top Bottom