Man of Honour
So I guess Titan (Black) and its Titan cooler would probably be the best way to go then I guess?
If it was me (no laughing please ) I would go with a couple of 290Ps for gaming and accept that I am going to have to compromise on the settings a bit.
I think this would be the smart money move as the OP could game at 4K for less than £600 spent on cards and wait for NVidia or AMD to launch something at a decent price with 6gb or 8gb of VRAM.
Other options
Titan Z, total joke for gaming (two Titan BEs beat it at everything).
Titan BE, you would need 3 to really use the VRAM and 4 on some games so not a serious option.
295X2, overpriced and rubbish performance compared to a pair of overclocked 290Ps.
290Xs, does not give much more that the 290Ps but there is a noticeable difference in cost.
So I think the OP would do well to play the waiting game and go with a couple of 290Ps (or even three).
The really important bit is how do your favourite games run @4K. My favourite game is Civ5 and it runs great maxed out @4K on a single stock 290X lol.
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