I only really play TF2 but it's happened with SWTOR as well and Prey.
Amazing, someone else still plays SWTOR

I had a similar problem, turned out to be the graphics card (AMD). Didn't suspect it because it was even happening on the desktop and nothing in the logs to suggest it. I think I fixed it going back to an older driver.
Also, if you use display port, maybe check the cable. I've heard it can cause weird issues.