'Best' all really depends on your personal needs, if you require a relatively secure backup storage solution then RAID 1 would be the ideal choice, however if you just require a general storage area and aren't too worried about potential data loss then JBOD will be fine.
Judging by results on here its not particularly worth going RAID0 over the other options.
If and when I get this I would most likely be using RAID1 as I want it to store my photos, music etc, so may have to stump up for some of the larger drives.