Regarding excel, I am still baffled why even experienced users that do not use the Power Query/Pivot continue with formula and macros, but maybe they stick to what they know.
I was thinking about seriously about using Power Query. I'm slightly nervous about MS changing licensing; I did some work in Flow/Power Autimate then some of the components went from free with the Office 365 licence to a different Tier that would have cost a lot more money and I didn't feel I could make a business case for.
The Pandas route promises to be very powerful and flexible; I'm looking forward to what I read is SQL-like functionality and much more.
We use power queries a lot. For throwing together a ton of data and doing some quick analysis and visual stuff they are great.