Dead easy to set up probes. You ideally want some kapton tape which you can find at popular online auction sites. Use that to stick the probe wherever you need to monitor. I have one stuck to each SSD since I couldn't read the temps off them once they were RAIDed - you can now though. I've also got one stuck to my pump's heatsink since DDCs have been known to get toasty under certain loads. You can also use software sensors (read off hardware monitoring) but these only work when Windows is running and the service is alive and well. The hardware sensors will work regardless of the state of Windows.
If you have a particularly long run, you can get 2-pin extensions. In theory they can affect the accuracy since the extra lead introduces a little extra resistance but it's usually negligible or you can set an offset to compensate.
For RGB you can use a Farbwerk and this will talk to the Aquaero. A Farbwek 360 will do RGBpx but (and apologies to mrh2019) I have nothing that uses RGBpx so can tell you almost nothing about those.
The
Quadro and
Octo are also worth being aware of as they have temperature headers, fan headers and RGBpx headers - so they could handle all of your requirements in one.....or they may fall irritatingly short. The fan headers only support PWM on the Quadro/Octo whereas the Aquaero 6 supports PWM (4-pin) or voltage control (3-pin) on all four channels.