yep, 'tis an option,
I've got two 3500-48's running the main office, so I'd agree if this was a blank sheet
Pros.
less gigastack links to get
less rack space
less to fail
Cons.
More users are down if it fails - I've got to keep two 24 port switches on standby in case one of the 48 port switches fails
Backplane bandwidth is shared over more users
A bit less flexible, to add one more user, I'd find it hard to justify another 48 port, it's a bit easier for another 24 port.
The patch cable wiring gets a bit congested.
If it was me with lots of nice 3550-24's, I'd just keep getting more of them.
I really like having the same kit whenever possible, it makes a network a lot easier to manage.
I'd rather see the 2900-24 kit completely removed from the server room rack and replaced with 3550-24's. That means he then has enough 2900-24's to re-use in buildings B & C
I used to have 6 brands of network switch, never mind dealing with different models as well

- simple is better.
.