I've generally found that 191x21 has required less voltage than 200x20, so that is what I would use. Lower voltages are always good as long as its stable, less heat generation etc.
You can leave pretty much everything on auto, one thing I'd suggest changing is the memory timing and voltage to what is on the side of the module and try to get the memory speed to under what the modules are rated for. So if it is 1600MHz modules then you want the divider that gives you approx 1528MHz. Also set the PCI-E clock to 100MHz and then change the vCore and QPI voltage as required. There is really no need to disable anything else imho.
There is a good guide here:
http://www.clunk.org.uk/forums/overclocking/22106-core-i7-overclocking-guide-beginners.html
Also make sure you stress test with Prime95 Blend and I also use LinX with All Memory selected. I use short bursts of each, so say 1 hour of Prime95 Blend and 30 minutes of LinX All Memory right after. If it passes both then there is a good chance it is stable, dial back the voltage and test again until you run into problems. Then go back up slightly and do longer runs. I use both again, one after another, they seem to create errors in different ways I've had something Prime95 blend stable for 8 hours and then fail LinX in 30 minutes and vise versa so hence my method.
If you get any BSOD, note down the code, eg 0x000124. If it automatically reboots before you can see the code it aso comes up in the little error box that pops up when you get back into Windows. Or disable automatic restart (Computer > Properties > Advanced system settings > Startup and Recovery Settings > Untick Automatically Restart). You can use these error codes to help with what needs changing using following link under X58:
http://www.overclock.net/general-pr...0091-complete-list-bsod-codes-when-ocing.html
80c is fine, anything sub 90c under load testing is fine, it won't hit that in normal use.