Bit late to the party, so apologies.
I had a similar custom loop setup to you OP.
- Trio X 4090 and 7950x on the same loop
- 1 x EK PE360 and 1 x EK XE360 Radiator with both in a Push configuration
- Had 6 x EK Vardar 120ER RGB Fans
- 2 x DDC Pumps in series as I had a lot of 90 degree fittings in my loop to manage, including a Distro Plate as well
- Flow Rate at 40% on both pumps was around 130L/HR when the PC was on idle. Would go up to 225L/HR during gaming sessions.
On idle and with fan speeds of around 500-600RPM, my Ambient Temps were around 23c and Water Temps were around 29-30c. At 800-900RPM, the delta would be around 4-5c.
With loads of around 550 - 600w (Combined CPU and GPU) during heavy gaming sessions, water temps would go up to around 42c and GPU would be around 60c with Fans around 1300RPM (60%).
I recently installed another 120mm Hardware Labs GTX 120 (54mm) Radiator in a push/pull at the rear of the case and it brings all the above temps down by around 2c during the same loads.
With thicker rads, ideally you want to setup a push/pull configuration if you can to help drive the heat out of the radiators. I would do it myself but I don't have the room in my case.
I now run my 4090 with an Undervolt of 0.945mv @ 2730Mhz with a +1500Mhz OC on the Memory, so my GPU and CPU rarely draws more than 420w total during gaming. That keeps the GPU at 46-47c and the Water at 33-34c.
From experience, I've found that EK GPU blocks can give you a water-GPU delta of around 15-20c. I've now bought blocks for a 6800XT, 3080Ti and 4090 and used the same setup as above and all fell within that delta range at really high loads (450-600w). However, if your GPU is jumping straight from idle temps to 60c immediately once you start a benchmark, that usually indicates a contact issue as the heat isn't efficiently being transferred out of the block.
Otherwise, I don't think you're doing much wrong in terms of optimising what you have for efficiency, you may just need more radiators and more fans to help keep your water temps down.