Thanks for the details Vince. Hope you can figure out how to make the Sata port work! Here's what I've gathered about ESXi X399 board compatibility thus far, hopefully it can help with your troubleshooting: 1) There appears to be similar installer PSOD issues with Gigabyte X399 AORUS Gaming 7 ( https://communities.vmware.com/thread/570854 ). 2) Youtube has a video showing the ASUS ROG Zenith Extreme X399 to be fully functional with ESXi without the need for any hacks ( https://www.youtube.com/watch?v=owQq2XmHiQg ). 3) Reddit contains a post with instructions for enabling GPU-passthrough on the ASUS Prime X399-A so I presume it should be functional too ( https://www.reddit.com/r/Amd/comments/72ula0/tr1950x_gtx_1060_passthrough_with_esxi ).