You absolutely could do that. For me the AIO cooler pipes are too short to reach the rear exhaust fan mount though, so it wouldn't work without modding anyway. And you would have to deal with the VRMs separately. And it would be overall more expensive. Besides water coolers only really move the heat from one place to another in a case, you still have to use fans to dissipate it, so I'm not really sold on the concept unless you need much higher cooling performance - which I don't. I did look at the Kraken G12 bracket to use a stock AIO CPU cooler instead, but, well, same issues listed above - and the G12 is hard to find in shops. Personally I just wanted it to be silent, cool and cheap, and on those three parameters combined I think it was the best option.