Additionally, is there any chance that this problem could be hardware related? As mentioned in the original post I've been encountering issues with my motherboard's top PCIE slot. Today, after initially installing the GPU in said slot, I booted and checked the GPU was properly powering on, but got no display. Nothing at all with either HDMI or Display port. After using a canister of compressed air and cleaning out the PCIE slot and then installing the GPU at a slightly different orientation I managed to get the GPU to properly display. Issue is that this is exactly what happened last time, I could use my computer just fine for the next day or so only to find on the third or fourth boot my GPU would fail to display. I am positive this issue is not a consequence of any problems with my Graphics card as it displays perfectly fine when using the second PCIE port. Perhaps the second PCIE slot is also suffering from a problem? All that said and done is it within the realm of possibility that a problematic motherboard could be causing the issue I am describing?