You need an eye test, seriously if you think that 1080p with 50% upscale looks better than native 1440p the is something wrong with your monitor or eyes. Its not even a 4:1 pixel upscale *eww*.
I was assuming he meant 2560x1440 DSR'd to 1080 compared to 2880x1620 DSR'd :S 2880x1620 DSR does not look better than 2560x1440 native I can tell ya that but those 1.5:1 DSR options do look quite good without the performance hit of going to double the resolution DSR though when the pixels are an exact multiplier you do get less oddities with text, etc. (obviously).
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