I'm using mark 5 ballistic weave military fatigues, mark 5 ballistic weave hat and a mixture of legendary pieces of combat armour and synth armour (all crafted as much as possible, of course). I have 308 ballistic, 315 energy and 40 radiation resistance. I could get more ballistic and energy resistance by using crafted sturdy or heavy pieces, but I like the collection of bonuses from the legendary pieces and I don't think having maybe 10% more ballistic and energy resistance would be as useful as those bonuses.
I am overpowered and playing to it. I'm roleplaying someone who wants to be the legendary founder of a country, so I want a suitably legendary reputation. Stroll into a supermutant camp, ring the bell on the counter and fire a few rounds to get their attention and stride through a hail of bullets to kill them all. 10 against 1? You'd better go fetch some backup, because the 1 is me.