In my youth it was said that the Sicilain (e4,c5) was played by players who were NOT prepared to to face The Kings Gambit (e4,e5,f4!).
If I played white, I usually chose the lazy option of d4. Against e4 as black, I'd usually reply with e5 and hope for the Spanish (Ruy Lopez). Bobby Fischer said that the "Kings Gambit was busted" but I never had an easy time defending it. I found it totally frightening!
Strangely enough, if I play on line chess at home against a computer, I've had more success as white with the Kings Gambit than any other opening. The computer will invariably opt for the accepted option rather than going for the declined variation, which usually gives white a more attacking game!
I might be wrong here, but I seem to remember that most high ranking games are drawn, white wins more games than black, but of the games played and won by black the Sicilian has the most successes!