Prescription meds from what I read.
Painkillers prescribed to him in the 2 weeks prior to his death, and the day before his death.
Not quite the rock and roll drugs death you were talking about.
Aye, and it can be quite easy to OD on some prescription meds, especially if you're not aware of the risks of taking too many or have a susceptibility to them, you just have to think of the number of people that don't realise how important it is to complete a course of anti-biotics, or what can reduce the effects of birth control pills.
For all we know Prince may have had a reaction to a combination of the painkillers and something else that was both legal and readily available.
There are all sorts of weird reactions you can get from some medications when taken with certain foods* or over the counter stuff.
My brother had a really nasty reaction to a prescription med when he was younger, it turned out it was something like only the second case the A&E consultant at the hospital had seen in 20 years, and the first time he'd heard of it on a dose as low as the one my brother was on.
So unless it turns out Prince was on a really high dose against his GP's advice I wouldn't put it down to "drugs"
Unfortunately it seems that in America/show business there are doctors that will prescribe dangerous levels of medication without proper instruction or supervision to big names.
*Simvastatin is one, you don't want to consume grapefruit whilst on it, as there is a reaction that whilst minor in many cases, it can be much worse in some.