You oc is in the bios not the hard drive.
The way I have my system is my 120Gb SSD as C with windows 7 64bit and all my games and software installed. I have used 50% of the drive and that perfect.
I then have a 2TB WD green drive as my data drive all my files, videos, work etc
Also make sure you put your windows temp folder on your 750Gb drive and other temporary files there as this will limit the number of writes on you SSD and thus increase life.