Its easy, but the ship would be massive-
http://en.wikipedia.org/wiki/Artificial_gravity#Rotation
"To produce 1g, the radius of rotation would have to be 224 m"
Thats not small!
And seeing as we cannot lift much into space in the first place, thats a lot of rocket trips with bits to be built in space.
Space ship construction yards are on the drawing boards, I've been told by a lecturer, to enable space exploration to be performed more easily, we could even be seeing one for the ESA Human Mars Mission in 2020.
If you can built a ship in space, it saves you a lot of effort, and could make it reusable, its would basically be like the IIS but with some engines, then with Pods to drop down to planet surfaces and come back up