I've been having real issues with both internal and external and external usb devices. Initially all was working fine. Then I had a problem with Intel RST which caused major issues and was only fixable with a reinstall of Windows (64bit). Sice then there have been USB problems. I have an internal card reader which recognises sd cards and non-Sandisk CF cards. Sandisk cards are not seen. I have an external card reader (Sandisk also) that only works with non sandisk products if they are inserted BEFORE the reader is attached via the usb cabe. An external hard drive is not always recognised and just recently a Corsair 16gb has gone funny. Yesterday when I inserted it the PC told me I had to format the drive, yet explorer still came up. I tried to copy all the files from the drive but it came up with 33hrs so I cancelled. I then tried to copy 1.5gb to the drive - 3hrs. Partway through it came up with the error - drive is inaccessable. Now I get a currupted drive error on every pc the flash drive is used in. I'm currently recovering the files with icare. I've tried installing new drivers and there's no drive letter conflicts. I'm at my wits end now. As an aside I also have the issue where, after sittle idle for a while, the hdd lights becomes constant for no reson and the pc slows to a crawl. Should I just give up and buy a prebuilt pc? 
System
i7 2600k oc to 4.3ghz - zalman cps10xtreme cooler
asus p8p67 deluxe
8gb corsair vengance downclocked to 1066
2x hd6950 with unlocked shaders but not oc'd
OCZ vertex 3 120gb for OS 2xsamsung 2tb for data
Sorry for the long first post, and if I've missed a thread solving this please point me the right way! Thanks!
System
i7 2600k oc to 4.3ghz - zalman cps10xtreme cooler
asus p8p67 deluxe
8gb corsair vengance downclocked to 1066
2x hd6950 with unlocked shaders but not oc'd
OCZ vertex 3 120gb for OS 2xsamsung 2tb for data
Sorry for the long first post, and if I've missed a thread solving this please point me the right way! Thanks!