whats the best way to set this up?

[iBot]

1x 250gig sata2 seagate 16mb cache
1x160 gig sata1 seagate 8mb cache

which drive should i use for windows and games? and which for storage?

 

[rpstewart]

The 250Gb drive is likely to be quicker (although only slightly) so I'd boot from that. Normally I'd use a 40-50Gb partition for Windows and installed programs then the rest for storage, that way you can reinstall without nuking data. Use the 160Gb for storage and the swap file.