I am going to say no chance. I dont think we have the funds for one, but more importantly Villa has been absolutely adamant for a number of years now that he really REALLY doesnt want to leave Spain (which doesnt surprise me considering the area he comes from).
I would still be very surprised if he moved anywhere exterior to Spain. Very surprised.
Probably his main contract/team in his whole career though, maybe he wants to be in England for his peak? Who knows. I don't get the feeling he'll leave Spain, especially not if Barca or Real offer him/Valencia anything at all.