I play 1440p with the scale at 100% all the time, I can only go to high settings if I want a stable 60fps.
Change around some settings such as mesh / shadows /reflections. AA especially, check your settings in Nvidia control panel too! I had my global settings set to force MSAA8x

Its all about the fine tune from here, don't forget there are updates/optimisations and driver releases to come so you might find you can activate more in the future. If you can live with high settings for now you will still be at a better clarity than 1080p thanks to your native resolution.
Try:
Mesh quality - High
Lighting quality - High
Effects quality - Ultra
Terrain decoration - High
Texture filtering - Ultra(Or high)
Texture quality - Ultra
with a mix of AA/Post process and hopefully 2xMSAA if you can, report back

Also OP there is a good chance you go SLI you WILL want to get a 120-144hz screen probably with Gsync, it will eliminate tearing, reduce your need to go with Vsync (Which you shouldn't be using at all EVER especially in an online FPS game) and allow you to actually make use of a 2nd card (Or be left with lots of OTT FPS that your screen cant use probably why you get tearing without Vsync now)
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