I'm using 2*m.2 and 3*SATA ports and the bottom 4x slot for a sound card and my GPU runs at 16x gen 4. The GPU only drop to 8x if you use the second 16x slot or the M2_3 slot.After installing everything it's all working very well now and I'm impressed how fast and smooth games are compared to my old system. The 7800X3D really is excellent. I feel like I'm getting the full potential out of my 4090 now, although saying that gpuz is saying my 16X cpu slot is running at 8x Maybes because I'm using the sata ports? But overall I'm very pleased with the upgrades.