OK will try to replicate the noise again tonight, I actually do think the noise is coming from the speakers because I was looking around the back of my monitor thinking "what the heck is that!?". I really hope it's not though, don't want to spend any more money on my rig and a £130 PSU isn't going to help.
Its difficult to recommend here but I will try.
My opinion is that the HX620 is not a high-end PSU, the Corsair AX line is their high-end line.
Is this causing your problem?
Hard to say, if its coming through the speakers, I would recommend you buy an upgraded one anyway.
Its possible that with that PSU and a single card GTX680 setup would be fine, however a GTX680 would draw around 350-400W max while benching which leaves 220W for everything else.
This is borderline for *some* setups.
If you are hearing it through your headphones when playing games, I would swap the PSU and cables for a better one.
If you are hearing it when you put your head next to the card, its more than likely either the card itself or a noisy power line.
Fixing that scenario could be harder.
I would also filter your power socket on the wall, make sure you don't use any 6-way plug extenders.
For the record I run a top-end Silverstone Strider 1500W and even I get coil whine from the cards (not through headphones), even when using a single card (even worse with 3!) but I think its my pretty white 3rd party cables which are probably more form than function.
I use a frame rate limiter to hold the cards back to 60 or 120fps, this helps with the whine.
I ran a Seasonic 500W previously with a single 5850 and got lots of coil whine through the speakers, it drove me nuts.