I don't think LvG actually wants to play this system, he'd much prefer to use wingers, but it's pointless considering how bad ours are. Januzaj and Di Maria would immediately give two great wide options. Every time Januzaj got the ball against Swansea he easily went past the full back and created something - he's only going to get better and better.
The Ajax team they used as an example is really quite different, having two dynamic central/defensive midfielders and then using wingers instead. The central midfielders and defensive midfielder can all cover the wide positions at will. It's similar to what Juventus do.
The balance of our team really isn't great, so as Neville said, the rest of the transfer window will dictate how we play for the season. Rojo can play centre back and left back, so he's useful (and required) regardless of whether we play 3 at the back or not, and that's it so far...