Someone on Reddit reckons it puts the IMC under more strain, running on 4, rather than 2 DIMMs:
"the memory controller has more strain keeping higher clocks with 4 sticks vs 2 sticks. You will either loosen timings to keep 4000mhz ram or lower ram frequency, which subsequently means lower FCLK."
Link;:
https://www.reddit.com/r/overclocking/comments/jsfo2o/5600x_47_2000mhz_fclk_4000mhz_but_only_with_2/
Need more info from AMD!
"the memory controller has more strain keeping higher clocks with 4 sticks vs 2 sticks. You will either loosen timings to keep 4000mhz ram or lower ram frequency, which subsequently means lower FCLK."
Link;:
https://www.reddit.com/r/overclocking/comments/jsfo2o/5600x_47_2000mhz_fclk_4000mhz_but_only_with_2/
Need more info from AMD!