At home we have 2 lionheads, which we got from a rabbit rescue place - they offered all sorts of advice and help, would never go to pets at home. We got a male and a female, but had them neutered/spayed, and they seem to get along nicely. We keep them in the kitchen, and they are fairly tidy, keeping most of their pooh in the litter tray and all their urine there, but you do find stray pellets around the door mat they like to sit on in the kitchen, and the occasional moist one elsewhere. I have to say ours aren't the most exciting rabbits ever - they don't mind being stroked/held for short periods, but tend to get a little restless after a while, and often just run away if you walk up to them. Lying on the floor can be fun though - they come and sniff all around before jumping up and sitting on you...
In general they are fairly low maintenance (food, water, litter tray, fresh hay, occasional clean up of hair in their corner, occasional inspection to check they're clean etc, trips for vaccinations etc are about it off the top of my head), very cute, sometimes a bit boring and shy, but nice to have around.