Well, the numbers are usually quoted tCL-tRCD-tRP-tRAS-Command per clock
The easiest change to make is to the Command per clock option. Earlier in this thread OC_A64 showed a 3% improvement in SuperPi by switching from 2T to 1T so if you can run at 1T, you should.
The next easiest number to tighten is the tRAS which is usually something horrendous like 31 on [AUTO]. Depending on you RAM spec. this will be either 12, 15 or 18 at PC6400 speeds. So try the specification figues first in all four numbers. eg. GeIL is 4-4-4-12. OcUK Value is 5-5-5-12.
In my experience you will be able to tighten the tRCD and tRP figures by 1 or possibly even 2 over the specification but usually you cannot tighten the tCL figure as that is what is tested when the RAM is speed binned at production. Some OcUK Value RAM will run at 4-4-4-12 with 2.1 or 2.2V through it, but not all. Some people have reported the Crucial Anniversaries will do 3-3-3-8 at 400MHz (PC6400), but mine won't. I can do 4-3-3-8-1T at PC6400.
Tweaking RAM on these boards is a begger of a job because, on my board at least, it requires a full CMOS reset when it goes wrong.
I made myself up an external CMOS reset switch from an old fan and a Single Pole, Dual Throw switch (£1.73 from my local high street electronics store). I just cut the fan cable off the fan. The 3-pin fan connector is the same 0.1" pin pitch as the jumpers. There are 3 pins on the switch, it doesn't matter which of the yellow or black cables you solder to the outer switch pins as long as the centre (red usually) cable is soldered to the centre pin on the switch. When the switch is thrown one way, it makes the NORMAL jumper position, when thrown the other way, it joins the RESET jumpers. For a tidy job you can drill out a PCI slot blanking pate and fix the switch into it. Who needs a £200 680i board for that? Not us! If anmyone is interested I might make up a thing for the case modding forum.