Iirc, PLX can actually cause a bit of latency compared to a full blown X series setup. I've ran dual card sli on several occasions on dual x8 pcie boards. From what I've read your not gonna notice the difference between dual x16 and x8. The only dual x16 setup I own is an X58 based 930 system. Bit old now so not a great chip to compare to current offerings tbh.