I had Grado SR60 for my pc (driven by santa cruz and the late 7050 AV receiver from kenwood) which were awesome but the centre orientated soundstage gave me headaches and the headphones were 100% uncomfy after 30 mins or more so I returned them and bought the Sennheiser HD485 - I will NEVER look back again, the sondstage is very nice and it engulfs you fully which is just what I need when watching movies, playing games and listening to acoustic music. The bass is on the same levels as the Grado too and after drive in period (almost 100 hours) sounds even better. Every detail is there. They are fairly new models though from Sennheiser so proper reviews may not be out yet.
SO in a nutshell, the HD485 vs Grado SR60 (and SR80 since they both are virtually identical bar the earpads which come with the SR80 which once put on the SR60 sound like the SR80...):
HD485 = Padded stand mountable on a shelf or table
HD485 = Very low sound leakage (SR60 could be heard from downstairs on medium volume)
HD485 = very comfy headband with a good half inch thick padding on underside (SR60 hs no padded headband)
HD485 = Nicer highs, feels more ronounced
HD485 = Wider soundstage
HD485 = Detachable single entry cable
HD485 = Around the ears fit as opposed to Grados "on the ears"
For mobile devices I use the Sony EX71slb that come with the w800i phone but I bought the HPM70kit (added mic extension) for my k750i and am quite happy with it thus far...I had the EX81SL but I prefer the 71s