Surely your meaning of universe is one giant void (i.e. "nothing", a.k.a a giant vacuum, as a vacuum is by definition nothing), containing matter and energy.
So therefore, once you've gone past the last planet/asteroid/molecule/atom/photon, you'll just keep going in the same direction and all you'll see is black nothing.
One philosophical question though, is how do we define "direction" ? We're all so used to "direction" using a fixed point on earth as a reference point, and we all use the sun as a reference point for the position of earth, solar system uses galaxy, galaxy other galaxies etc. But how do we know we are ever moving in a straight line? What if galaxies travel in curves or other weird directions?
So I think the real question is, how can we ever be sure we would ever reach the "end" of the universe? How do we know for sure we are travelling in a straight line?
And another fundamental question is, what allows a vacuum to exist? Does this vacuum have to exist being contained inside something else? Before the big bang, was there a big vacuum, or was there literally "nothing", not even a void (although "no void" should suggest something does exist).
One last important note to mention is, the word "universe" in itself is defined as
everything in existance. Whether that includes empty void space or not, I'm not sure. So to ask "is there anything beyond the universe" is like asking "does anything exist outside the realm of existance?" Which is not really answerable
