Yes, I have fused lumbar #5 and a herniated disc in my upper back before my neck.
I've given up on running and the gym as a result and returned to cycling.
Just been on a wet windy test ride on the Allez, It felt strange having such a tight head angle at first, the front wheel right under me, however it handles very well and corners well despite poor road conditions.
No issues with toe overlap.
The frame is surprisingly compliant and I enjoyed riding it.
Sora groupset is the absolute lowest I would ever want to go, it works well, but feels clunky and un refined.