There is no straight forward guide for madvr as so many things impact the settings i.e.
- source of the video being the main thing, be it a poor quality encode or/and 720 VS 1080 VS 4k, bit rate etc. etc.
- what res. the display is that you are viewing said material on
- type of content i.e. anime?
- GPU power you have
etc. etc.
Not to mention there are different preferences for image quality i.e. some might like a very sharp look where as others will prefer a more natural/softer look.
This is a good basic guide for a quick setup here, although very out of date:
http://www.avsforum.com/forum/26-home-theater-computers/1357375-advanced-mpc-hc-setup-guide.html
And then these:
https://forum.doom9.org/showthread.php?t=171787
http://forum.kodi.tv/showthread.php?tid=259188
Everything else is left at default settings except I have smooth motion turned on.