Same motherboard as you. Was it asking you to restart or was it not changing anything till you restarted? A couple of my observations.
Did you notice that the chipset drivers are much bigger from msi then they are directly from amd? Dunno why this is.
I wasn't convinced Amd master was evening doing anything. Only gave it a quick go as I though it might save time from rebooting constantly whilst trying out overclocks.
This is the message i currently get when trying to apply oc settings
Beforehand that would never show up, it would basically apply the settings on the fly in windows and you could get straight to testing them. Last night for a while it was applying settings without the need for reboot, now today its back to the above. Only reason i'm using this program is my motherboard suffers from a weird bug that many have reported where if you go over default voltage the cpu sticks at 1550 mhz or thereabouts. I re-flashed my bios a few times and it still seems to do this so i just use the ryzen program for the time being.
The driver size i thought was to possibly do with it maybe including radeon drivers as well? Not really sure why its so ridiculously large in size.
And since last night the mobo has been displaying another "oddity" where when the system reboots to apply the ryzen master settings it constantly goes into the bios instead of loading up windows, and it take a lot of fart assing about changing random settings to get it to boot up into windows again. I'm honestly considering returning this and going for something different as it just seems to have a lot of bugs that need worked out.