I have the CPU fans on Standard, using CPU as source, side fans on static speed (using M/B as source leaves fans static from what I noticed), and bottom intake on Quiet using CPU as source. When Im gaming my Strix 1080ti makes more noise on 55-60% fan speed than my actual PC fans.
I'll give your settings a try. Makes sense. There's a lot to tinker with on these new boards, my old socket 1155 motherboard had sod all you could change in comparison. Very pleased with it so far. If my 32GB (2x16) Ballistix kit performs well I think I'll be set for years to come with just the odd GPU upgrade.