@Middenacht - DSC should be enabled by default when you select a > 144hz refresh rate at 4k for your monitor via Nvidia control panel.
It’s DSC switching ‘on and off’ that’s the problem that you want to avoid. In my personal use case, my monitor will ‘turn off’ for 2/3 seconds just like I am selecting another input. This happens at seemingly random intervals with my (160hz max) monitor running >144hz at 4k via display port 1.4.
It’s impossible to be sure what is causing this, but I’m pretty sure windows and the monitor are getting confused as to what level of DSC is required and then it’s recalibrating as it goes. When you’re running at 240hz, this might be less common as windows / monitor already knows it will have to use a ‘relatively compressed’ DSC.
Have a google for ‘alt + tab’ and DSC issues and you’ll get a feel for the sort of nuisances that people run into.
With all of this said, most people don’t seem to run into major issues. But for me personally if there was a choice between a monitor with DP2.1 with the full 80gb/s bandwidth or not, I’d be going with the full DP2.1 for these reason.
As mentioned, the MSI 322URX seems to be another model that offers this.