Crits are probably the only one absolutely worth taking. It increases your XP gain, nothing else will have any massive effect on how much experience you can gain, and are quality of life improvements.
If you could change them on the fly it would completely break the fact that predator and combat sections are separate. They could perhaps have moments to reselect, but you're still really close to the start. Right now I'm holding onto one because the upgrades available to me aren't that exciting, so I'd rather see what else comes up when I unlock the next bit of the tree. I've already bought upgrades that I'd not mind not having either, but lvls aren't too far and few between. At least if you try and maximise things (try all gadgets in every fight, as long a combo as you can, all skills etc).
I finished the game yesterday and I think I see why there isn't an option to respec now. You get enough points to buy most skills just playing normally and imo no skill is essential, just nice to have. I plan to replay this again soon.
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