At the moment I’ve got bottom and side as intakes and top and back as exhaust. Before I vertically mounted the gpu would sit around 65c on load on cpu (3700x) would be in the mid 50’s, vertical mount actually helped with airflow gpu now around 60-62c and cpu is 50-52c under load with the occasional ryzen spike up to 60c and then back down again. I’m waiting for a 5900x which should turn up any day now going to do some of my own testing and possibly swap the top fans for intake and see if that makes a difference to cpu temps. The setup I run currently is actually one that I also saw on a video that suggested it was the best way of running it. I guess realistically there’s no wrong way of doing it it’s just all down to personal preference. And I guess it also depends on how much fan noise you can put up with before it drives you mad I’ve got 11 be quiets in there! lol
Ive got a ryzen 9 3900x, a corsair 150i 360mm aio (with 3 x LL120 rgb on it), 4 x 16gb corsair vengeance rgb pro, 2 x pcie4 nvme, 6 other LL120 rgb corsairs, a bequiet 80mm silent wings and sadly as i couldnt find and sensibly priced replacements my 5 month old RTX 2070 super gpu in a vertical phanteks mount to cram in there over the next week or so.
This video from Chris shows some very good stats of his results which showed lowest temps running the bottom as input, aoi top as input and side as output.
I suspect this is because he had a normal mounted gpu card which is blocking most of the intake from the bottom and why he needed intake from the top to get decent cpu temps with a cold supply coming in through the top.
This second video shows the best temps when running bottom and side as intake and top as exhaust.
So some opposites there, but none are running vertical gpu mount, or an 80mm exhaust on the back (or 2 in your case), both of which would postively impact temps i think. It is worth mentioning that the rad would probably function better pulling cold air through so it cools the water inside with a cool supply of air, rather than pushing hotter case air through it (several videos also support this).
apologies for the thread hijack, I have built both my sons gaming pcs in the 500dx, a fine case, sooooo quiet (used bequiet cooler as well), only bits i didnt like was some average build quality in some places of the case and not a great deal of room - so i went for the lian li myself.