The "too well educated" thing has been busted. It's because there are not enough workers near the industry itself, as we usually dump industry as far away from residential as we can.
Absolutely epic mate, amazing work. Can I ask what how many lanes the majority of your roads are, because at that size, it must be hell in there.

Where was it "busted", based on my observations its true.
Good transport links? I'm only reporting what I was reading on /r/citiesskylines when people kept asking about why there were not enough workers.
Can it be done?
Why do roads never place, well hardly enough go straight sometimes they are slightly wonky and does my head in! Even from starting a new games linking a road doesnt look straight, am I doing something wrong!?
Good transport links? I'm only reporting what I was reading on /r/citiesskylines when people kept asking about why there were not enough workers.
Just to elaborate on my own experience, now I've got more time to post.
In a new area I built an industrial zone, and fairly close by a residential zone (not right next to it but close and with great transport links). I didn't build any schools in this area. Industry mostly had enough workers though a few were complaining. I cranked down the education budget and after some time it all seemed good. I then built loads of schools and cranked up the budget for good measure, I now have pretty much every industrial building complaining about a lack of workers and half the buildings abandoned. Nothing has changed besides education.
For some reason I'm not getting this game. I fail at it badly, I run out of cash and I'm on my 6th city and I have not managed to reach 4000 ppl. Any pointers?
Sounds like the education 'engine' makes everyone of a higher quality and therefore not suitable for that industry, perhaps like in real life, they need to have a percentage of lower performers and higher performers (low city/area educations = higher percentage of lower educated; high city/area education = higher percentage of higher educated but still with low educated people).
Yeah, exactly this.
Every job tells you exactly what sort of worker you need, offices favour high education, industry wants low/no education. For every citizen you educate, you're taking a potential worker from industry.
When they're saying theres no workers, they mean 'suitable workers', if every person is a genius and they need mindless drones, they're screwed.
What i find works best is to often create an industrial area and an area for residential & commercial where they're not given access to schooling. By creating them at the same time, what tends to happen is the 'job for life (unless workplace is destroyed)' means that the person moves into the area and theres new work nearby in need of uneducated people.
If you build a huge industrial area and no new homes, you'll end up pulling people from existing homes across the map, and they'll have to travel that distance to get to work - more traffic.
