You can, but the whole point is really to group up and quest/pvp together. It isn't really a single player game like Skyrim or The Witcher.
Actually this is the best mmo to play solo, there is really no reason to group up to do events/hearts etc other than social reasons. Also if you like to play solo and end up needing help with something, a lot of the maps seem to have very social players who are helpful and friendlily, specially ones with big dragon boss events on them.
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