My overclocks with CCC installed were significantly lower than without it. I remember strugging to get past 1150MHz until CCC was removed, and then the card went all the way up to 1275MHz stable with fan on 100%.
I think CCC somehow prevents voltage adjustments being applied, because 1150MHz was about all I could get on stock volts without CCC. My card has now gone to it's new owner (it was a new system build for a friend), so I cannot test further.
1200MHz/5800MHz was it's final 24/7 clocks @ 1.15v (CCC removed). New owner has been very very happy with it. His system was built for WoW and BF3, and the upgrade from a 4890 has been huge.
edited to say: My card did not like >1.2v. Even on low clocks >1.2v would cause slow downs. It seems that without CCC overvolt protection cuts in, but with it you cannot adjust voltages correctly. It would be nice if GPU had the slider to get around OVP.
Might give that a go.
I just have one issue with no using CCC - I use the presets with hotkey to swap between my monitors, as I don't use both at same time.
Any other option for me doing this?